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Lab markers (fasting glucose, insulin, lipid panel) typically show meaningful improvement
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Not as potent as clonidine as antihypertensive Amitryptyline (TCAs) decrease REM sleep % but tolerance may develop to REM suppression with a marked rebound following drug withdral Mirtazepine : potent 5-HT2 and 5-HT3 antagonist (antinausea)
Given how many other bodily factors can cause these same symptoms, the thyroid might be the last place that an individual thinks to look when they are not feeling well
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